Related Experiment Video
Updated: Jul 18, 2026

Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application
Published on: March 8, 2019
Interaction with intraocular lens materials: does heavy silicone oil act like silicone oil?
Aylin Yaman1, A Osman Saatci, Sulen Sarioğlu
1Department of Ophthalmology, Dokuz Eylul University, Izmir, Turkey.
Purpose:
To determine the interaction of heavy silicone oil with various intraocular lens (IOL) materials and whether heavy silicone oil covers the silicone IOL optic as silicone oil does.
Setting:
Department of Ophthalmology, Dokuz Eylul University, Izmir, Turkey.
Methods:
The study group comprised 5 poly(methyl methacrylate) (PMMA) IOLs, 4 foldable silicone IOLs, 5 foldable hydrophilic acrylic IOLs, and 5 foldable hydrophobic acrylic IOLs. Each IOL was bathed in balanced salt solution (BSS) for 10 minutes and then placed in heavy silicone oil dyed with Sudan Black for another 10 minutes. Afterward, each IOL was reimmersed in BSS for 5 minutes and examined under the light microscope. Digital images were analyzed to determine the optic area covered with heavy silicone oil.
Results:
The mean heavy silicone oil coverage was 7.05% +/- 7.88% (SD) (range 1.13% to 20.54%) on PMMA IOLs, 100% on silicone IOLs, 12.17% +/- 11.43% (range 1.25% to 31.52%) on hydrophobic acrylic IOLs, and 34.64% +/- 13.28% (range 12.57% to 44.42%) on hydrophilic acrylic IOLs. Heavy silicone oil coverage of silicone IOLs was statistically significantly greater than the coverage of other IOL materials.
Conclusion:
Heavy silicone oil acted the same as silicone oil and covered the entire surface of silicone IOLs.
Related Concept Videos
Design Example: Deciding Thickness of Lubricating Fluid in a Shaft
To calculate the required thickness of the lubricant layer, the tangential velocity at the shaft's surface must first be determined. This velocity is calculated by converting the rotational speed to angular velocity...
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
Ophthalmic Drug Delivery Systems
Imaging Biological Samples with Optical Microscopy
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
Angle Closure Glaucoma: Treatment

