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Updated: Jul 18, 2026

Microscopic Replantation of Penile Glans Amputation Due to Circumcision
Published on: June 3, 2022
[Metastatic Crohn's disease involving the penile foreskin]
Rosa María Jiménez Rodríguez1, Enrique Argüelles Solido, David Marcilla Plaza
1Servicio de Urología, Hospital Universitario Virgen del Rocío, Sevilla, España. ros_j_r@hotmail.com
Objective:
To describe the case of the patient with history of Crohn's disease presenting metastatic extension to the penile foreskin.
Methods:
Circumcision was carried out and the skin was sent to the pathology department.
Results:
Pathologic study of the specimen showed an ulcerated granuloma without caseum, typically associated with metastatic Crohn's disease. After one year of follow-up there is no evidence of recurrence.
Conclusions:
Crohn's disease is a disease of unknown origin, the main characteristic of which is the development of non necrotizing granulomas that may involved not only the gastrointestinal tract. When the extraintestinal involvement is not produced by continuity we call it metastatic disease. Such metastases may be found in the genitourinary tract, and other sites. This involvement may include lithiasis, amyloidosis, ... and the presence of lesions in the genital skin, as in our case.
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