[Supraglottic horizontal partial laryngectomies in 163 cases]

Area of Science:

• Otolaryngology
• Surgical Oncology
• Laryngeal Cancer Research

Background:

• Supraglottic laryngeal carcinoma presents a significant challenge in head and neck oncology.
• Evaluating surgical interventions is crucial for improving patient survival and laryngeal function.

Purpose of the Study:

• To assess the clinical efficacy and functional outcomes of supraglottic horizontal partial laryngectomy.
• To determine the survival rates and recurrence patterns associated with this surgical technique.

Main Methods:

• A retrospective analysis of 163 patients with supraglottic laryngeal carcinoma treated between 1978 and 1998.
• Surgical techniques involved modified horizontal partial laryngectomy with specific reconstruction methods.
• Survival analysis utilized the Kaplan-Meier method, with stage differences tested by the Los-Rank method.

Main Results:

• Five-year survival rates varied significantly by stage (I-IV: 100% to 33.3%) and nodal status (cN0: 73.1%, cN+: 45.5%).
• The procedure demonstrated good speech and swallowing function post-operation with a 91.4% decannulation rate.
• Major causes of mortality included cervical lymph node metastasis (40%) and laryngeal recurrence (18%).

Conclusions:

• Supraglottic horizontal partial laryngectomy is highly effective for disease eradication and laryngeal function preservation when indications are carefully selected.
• Selective lateral neck dissection is advised for patients with supraglottic carcinoma to manage potential metastasis.