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Updated: Jul 18, 2026

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
Clerodane diterpenoids from Salvia splendens
Gianfranco Fontana1, Giuseppe Savona, Benjamín Rodríguez
1Dipartimento di Chimica Organica E. Paterno, Università degli Studi di Palermo, Parco d'Orleans 2, I-90128 Palermo, Italy.
Abstract:
Four new clerodane diterpenoids, salvisplendins A-D (1-4), have been isolated from an acetone extract of the flowers of Salvia splendens, together with an artifact (5), arising from salvisplendin D (4) by addition of diazomethane, and the already known clerodane olearin (6). The structures of the new compounds (1-5) were established mainly by 1D and 2D NMR spectroscopic studies and, in the case of salvisplendin A (1), by chemical correlation with splenolide B (7). Complete 1H and 13C NMR assignments for olearin (6), not published hitherto, are also reported.
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