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Endoluminal fundoplication.

Michele Marchese1, Cristiano Spada, Guido Costamagna

  • 1Digestive Endoscopy Unit, Catholic University of Rome, Largo Francesco Vito 1, 00168 Rome, Italy.

Minimally Invasive Therapy & Allied Technologies : MITAT : Official Journal of the Society for Minimally Invasive Therapy
|December 28, 2006
PubMed
Summary
This summary is machine-generated.

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Endoscopic antireflux procedures offer an alternative for GERD patients unresponsive to medication. Sewing techniques show clinical benefits like reduced PPI use, though esophageal function improvements are limited.

Area of Science:

  • Gastroenterology
  • Minimally Invasive Surgery

Background:

  • Gastroesophageal reflux disease (GERD) poses challenges when standard treatments fail.
  • Anti-reflux surgery may not be suitable for all GERD patients.
  • Endoscopic antireflux procedures present an alternative therapeutic avenue.

Purpose of the Study:

  • To evaluate the efficacy of endoscopic antireflux procedures in GERD management.
  • To assess outcomes of sewing techniques in comparison to other endoscopic methods.

Main Methods:

  • Review of available endoscopic antireflux procedures, including sewing, injection/implant, and radiofrequency.
  • Analysis of clinical results focusing on symptom improvement and medication reduction.
  • Evaluation of changes in esophageal manometry and acid exposure time.

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Main Results:

  • Sewing techniques demonstrated positive clinical outcomes in GERD patients.
  • A reduction in proton pump inhibitor (PPI) consumption was observed.
  • Significant improvements in esophageal manometry and acid exposure were noted in only a subset of patients.

Conclusions:

  • Endoscopic sewing techniques offer a viable option for GERD patients with refractory symptoms.
  • While clinical symptom improvement is achievable, objective esophageal function changes are less consistently observed.