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Randomized, Triple-Blind, and Parallel-Controlled Trial of Transcranial Direct Current Stimulation for Cognitive Rehabilitation after Stroke
Published on: June 6, 2025
Randomized clinical stroke rehabilitation trials in 2005
1Burke Rehabilitation Hospital, Weill Medical College of Cornell University, 785 Mamaroneck Avenue, White Plains, NY 10605, USA. mrabadi@burke.org
Neurochemical Research
|December 28, 2006
Summary
This review covers 31 randomized control trials (RCTs) from 2005 on stroke rehabilitation treatments. Studies evaluated medications, devices like robots, and therapies for improving function and motor recovery post-stroke.
Area of Science:
- Neurology
- Rehabilitation Medicine
- Clinical Trials
Background:
- Stroke rehabilitation is crucial for patient recovery.
- Evidence-based practice relies on rigorous research, such as randomized control trials (RCTs).
- Identifying effective interventions is key to optimizing post-stroke outcomes.
Purpose of the Study:
- To review and synthesize findings from RCTs conducted in stroke rehabilitation during 2005.
- To assess the efficacy of various interventions aimed at improving function and motor recovery after stroke.
Main Methods:
- A comprehensive Medline search was conducted.
- The search focused on English-language RCTs published in 2005 related to stroke rehabilitation.
- 31 relevant RCTs were identified and analyzed.
Main Results:
- Efficacy of medications like folate, vitamin B12, and bisphosphonates in preventing hip fractures was examined.
- Studies investigated compression stockings for deep vein thrombosis (DVT) prevention.
- The use of mechanical robots, upper limb positioning, transcranial magnetic stimulation, acupuncture, and neural tissue transplantation for motor recovery was evaluated.
Conclusions:
- The reviewed RCTs explored a diverse range of interventions for stroke rehabilitation.
- Findings provide insights into the efficacy of pharmacological, technological, and therapeutic approaches.
- Further research is needed to confirm and refine these interventions for clinical practice.
