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Polymer membrane electrodes for sensitive potentiometric determination of beta-blockers

Anwar A Wassil1, Abd El-Ftaah Bastawy Farag, Fatma A Moukdad

  • 1National Organization for Drug Control and Research, Cairo, Egypt.

Drug Development and Industrial Pharmacy
|December 29, 2006
PubMed

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Reference electrodes serve as a stable reference point for potentiometric measurements, while indicator and working electrodes react to variations in the composition of a solution.
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Potentiometry is an analytical technique that measures the potential difference between two electrodes in an electrochemical cell without drawing any significant current that could alter the solution's composition. This method employs an indicator electrode, which exchanges electrons with the analyte solution, and a reference electrode with a constant potential. Each electrode is immersed in a solution comprised of two half-cells. In a conventional setup, the reference electrode serves as the...
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The chosen potential ensures...
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Potentiometric titration is a quantitative analytical technique that determines the concentration of an analyte by measuring the potential difference between the two electrodes in the solution. The endpoint of a potentiometric titration is the point at which there is a significant change in the potential difference. It occurs when the stoichiometric reaction between the analyte and the titrant is complete. The endpoint is usually determined graphically by plotting the measured potential...