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Related Concept Videos

Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.

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Updated: Jul 18, 2026

Nanoscopic Imaging of Human Tissue Sections via Physical and Isotropic Expansion
09:11

Nanoscopic Imaging of Human Tissue Sections via Physical and Isotropic Expansion

Published on: September 25, 2019

Nanoscopic medicine: the next frontier.

Reiner Peters1

  • 1Institute of Medical Physics and Biophysics, University of Münster, Robert-Koch-Strasse 31, 48149 Münster, Germany. Reiner.Peters@uni-muenster.de

Small (Weinheim an Der Bergstrasse, Germany)
|December 29, 2006
PubMed
Summary

This study introduces nanoscopic medicine, integrating live cell nanoscopy with nanoscopic protein machine (NPM) analysis for disease diagnosis and therapy. It enables direct visualization and modification of cellular components for advanced medical treatment.

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Biomolecular Imaging of Cellular Uptake of Nanoparticles using Multimodal Nonlinear Optical Microscopy
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Last Updated: Jul 18, 2026

Nanoscopic Imaging of Human Tissue Sections via Physical and Isotropic Expansion
09:11

Nanoscopic Imaging of Human Tissue Sections via Physical and Isotropic Expansion

Published on: September 25, 2019

Biomolecular Imaging of Cellular Uptake of Nanoparticles using Multimodal Nonlinear Optical Microscopy
07:13

Biomolecular Imaging of Cellular Uptake of Nanoparticles using Multimodal Nonlinear Optical Microscopy

Published on: May 16, 2022

Area of Science:

  • Cell Biology
  • Nanotechnology
  • Medical Diagnostics

Background:

  • Recent advancements in cell science and optical nanoscale microscopy have paved the way for medical nanoscopy.
  • Understanding cellular mechanisms at the nanoscale is crucial for developing novel diagnostic and therapeutic strategies.

Purpose of the Study:

  • To propose a comprehensive diagnostic and therapeutic scheme, termed nanoscopic medicine.
  • To integrate live cell nanoscopy with the study of nanoscopic protein machines (NPMs) for medical applications.

Main Methods:

  • Live cell nanoscopy for real-time cellular observation.
  • Structural and functional studies of nanoscopic protein machines (NPMs).
  • Systems biology approaches, fluorescent labeling, nanoscopic analysis, and nanoscopic intervention techniques.

Main Results:

  • The proposed nanoscopic medicine framework aims to explore the nanoscopic foundation of cells.
  • It facilitates the direct visualization, analysis, and modification of NPMs and their networks within living cells and tissues.

Conclusions:

  • Nanoscopic medicine represents a novel frontier in healthcare, moving towards the fundamental nanoscale of cellular processes.
  • This approach holds potential for the diagnosis and therapy of diseases by targeting NPMs.