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Published on: August 26, 2018
Radical-scavenging activities of new hydroxylated ursane triterpenes from cv. Annurca apples
Brigida D'Abrosca1, Antonio Fiorentino, Pietro Monaco
1Dipartimento di Scienze della Vita, Seconda Università degli Studi di Napoli, via Vivaldi 43, I-81100 Caserta.
Abstract:
Two new ursolic acid triterpene derivatives, compounds 2 and 3, have been isolated from cv. Annurca apple fruit, a high-quality apple variety widely cultivated in southern Italy, together with the known 2-oxopomolic acid (1). The new compounds were identified by means of different spectroscopic techniques as 3-epi-2-oxopomolic acid (= (3alpha)-3,19-dihydroxy-2-oxours-12-en-28-oic acid; 2) and (1alpha)-1-hydroxy-3-oxours-12-en-28-oic acid (3). Compounds 1-3 were tested for their radical-scavenging activities with the aid of a 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay (Fig. 2). All three constituents showed activities similar to that of the reference antioxidant alpha-tocopherol (vitamin E).
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