Related Experiment Video

Updated: Jun 22, 2026

Methyl-binding DNA capture Sequencing for Patient Tissues
08:40

Methyl-binding DNA capture Sequencing for Patient Tissues

Published on: October 31, 2016

Mining methylation for early detection of common cancers

Romulo M Brena1, Christoph Plass, Joseph F Costello

  • 1Department of Molecular Genetics, The Ohio State University, Columbus, Ohio, United States of America.

Plos Medicine
|December 30, 2006
PubMed
Abstract

No abstract available in PubMed .

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Epigenetic Regulation01:46

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Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
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Epigenetic Regulation

Epigenetic changes alter the physical structure of the DNA without changing the genetic sequence and often regulate whether genes are turned on or off. This regulation ensures that each cell produces only proteins necessary for its function. For example, proteins that promote bone growth are not produced in muscle cells. Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
X-chromosome...