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Updated: Jul 18, 2026

A Cell Culture Model for Producing High Titer Hepatitis E Virus Stocks
Published on: June 26, 2020
[Autochthonous hepatitis E in France]
Yves Buisson1, Elisabeth Nicand
1Institut de Mèdecine tropicale du Service de santé des armées, B.P. 46, 13998 Marseile Armées.
Abstract:
Hepatitis E must no longer be considered simply as an exotic disease occasionally imported from developing countries. Autochthonous hepatitis E exists in France. In spite of certain difficulties and limits, biological markers of hepatitis E have to be included in algorithms for etiological diagnosis of acute hepatitis, even if the patient has not recently traveled abroad. Based on a recombinant protein of the viral capsid, more sensitive serological assays should soon be available. The potential severity of hepatitis E, especially during pregnancy, calls for a national surveillance program, including evaluation of the animal reservoir and the risk associated with drinking water and food.
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