Psychiatric adjustment in the year after meningococcal disease in childhood

Daniel Shears1, Simon Nadel1, Julia Gledhill1

  • 1Drs. Shears, Gledhill, and Garralda are with the Imperial College London, Academic Unit of Child and Adolescent Psychiatry; Dr. Nadel is with the St. Mary's Hospital, London; and Dr. Gordon is with the Imperial College London, Statistical Advisory Service.

Insights

Psychiatric disorders are common in children following meningococcal disease, with over half experiencing issues in the year after illness. Severe illness and pre-existing behavioral problems increase this risk.

Area of Science:

  • Pediatric infectious diseases
  • Child and adolescent psychiatry
  • Neuropsychology

Background:

  • Meningococcal disease can have significant long-term health consequences.
  • The psychiatric impact of meningococcal disease in children requires further investigation.

Purpose of the Study:

  • To evaluate the psychiatric status of children after experiencing meningococcal disease.
  • To identify risk factors associated with developing psychiatric disorders post-illness.

Main Methods:

  • A cohort study involving 66 children (ages 4-17) admitted for meningococcal disease.
  • Psychiatric disorders were assessed using standardized interviews and questionnaires at 1-year follow-up.

Main Results:

  • 57% of children aged 6+ experienced psychiatric disorders within a year of discharge.
  • Common disorders included depression, oppositional defiant disorder, and anxiety.
  • Illness severity, shock on admission, and premorbid behavioral issues predicted later psychiatric conditions.

Conclusions:

  • Psychiatric disorders are a frequent outcome in the year following meningococcal disease in children.
  • Children with severe meningococcal illness and pre-existing emotional/behavioral problems are at higher risk.
Abstract

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