Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Error-processing deficits in patients with cocaine dependence.

Ingmar H A Franken1, Jan W van Strien, Ernst J Franzek

  • 1Institute of Psychology, Erasmus University Rotterdam, Woudestein J5-43, PO Box 1738, 3000 DR Rotterdam, The Netherlands. franken@fsw.eur.nl

Biological Psychology
|January 2, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reliability of Electrophysiological Measures of Cognitive Control and Sociodemographic Correlates in a Large Adolescent and Emerging Adult Cohort.

Psychophysiology·2026
Same author

Which personality traits are necessary conditions for problematic alcohol use? Insights from a 23-year longitudinal study.

Addiction (Abingdon, England)·2026
Same author

Sexual hallucinations and delusions in borderline personality disorder.

Frontiers in psychiatry·2026
Same author

Navigating Opportunities and Challenges in Large-Scale Longitudinal Electroencephalography Studies.

Biological psychiatry global open science·2026
Same author

Adolescent Risky Alcohol Use Is Associated With Electrophysiological Markers of Error Processing: Findings From a Large Cohort Study.

Biological psychiatry global open science·2025
Same author

The uncertain path to reward: Neural mechanisms of intolerance of uncertainty in reward processing.

Cortex; a journal devoted to the study of the nervous system and behavior·2025

Cocaine addiction is linked to impaired error processing, evidenced by reduced brain responses (ERN/Pe) and poorer behavioral correction after mistakes. These deficits may sustain addiction by affecting cognitive control.

Area of Science:

  • Neuroscience
  • Psychology
  • Addiction Research

Background:

  • Cocaine addiction involves persistent use despite negative outcomes.
  • Error processing is a critical cognitive function potentially affected in addiction.

Purpose of the Study:

  • To investigate error processing deficits in cocaine-dependent individuals.
  • To measure error-related negativity (ERN) and error positivity (Pe) in cocaine addiction.

Main Methods:

  • Event-related potentials (ERPs) were recorded during an Eriksen flanker task.
  • Cocaine-dependent patients were compared to a healthy control group.

Main Results:

  • Cocaine-addicted patients exhibited diminished ERN and Pe components.

Related Experiment Videos

  • Behaviorally, patients showed reduced accuracy improvement following errors.
  • These findings indicate compromised error processing and behavioral correction.

    • Conclusions:

    • Cocaine addiction is associated with significant error processing deficits.
    • Impaired cognitive control and error correction may contribute to addiction maintenance.
    • Deficits may stem from a compromised dopamine system.