Myocardial damage in high-risk patients undergoing elective endovascular or open infrarenal abdominal aortic aneurysm repair
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Updated: Jul 18, 2026

A New Murine Model of Endovascular Aortic Aneurysm Repair
Published on: July 7, 2013
O Schouten1, M Dunkelgrun, H H H Feringa
1Department of Vascular Surgery, Erasmus MC, Rotterdam, The Netherlands.
Insights
Endovascular repair of abdominal aortic aneurysms (AAA) in high-risk patients significantly reduces perioperative myocardial damage compared to open repair. Dobutamine stress echocardiography (DSE) identified similar cardiac risk in both groups.
Area of Science:
- Cardiovascular Surgery
- Vascular Surgery
- Cardiac Imaging
Background:
- Dobutamine stress echocardiography (DSE) objectively assesses coronary artery disease.
- Patients undergoing infrarenal aortic aneurysm (AAA) repair often have high cardiac risk.
- Comparing open vs. endovascular AAA repair outcomes in high-risk patients is crucial.
Purpose of the Study:
- To compare cardiac outcomes in high-risk patients undergoing open or endovascular infrarenal AAA repair.
- To utilize preoperative Dobutamine stress echocardiography (DSE) results for risk stratification.
- To evaluate perioperative myocardial damage and major adverse cardiac events.
Main Methods:
- Retrospective review of 77 high-risk patients (>or=3 cardiac risk factors) undergoing infrarenal AAA repair.
- All patients underwent preoperative Dobutamine stress echocardiography (DSE).
- Postoperative data collected included troponin levels, ECG, and major adverse cardiac events up to 30 days.
Main Results:
- 77 patients (39 endovascular, 38 open) with pre-existing cardiac disease were analyzed.
- Preoperative DSE showed similar levels of myocardial ischemia between open and endovascular groups.
- Endovascular repair was associated with significantly lower perioperative myocardial damage (13% vs. 47%, p=0.001) and fewer major adverse cardiac events (0% vs. 13%, p=0.02).
Conclusions:
- Endovascular AAA repair is associated with reduced perioperative myocardial damage in high-risk patients.
- DSE findings were similar between groups, highlighting the benefit of endovascular repair.
- This suggests endovascular repair may be a safer option for infrarenal AAA in patients with high cardiac risk.
Objective:
Dobutamine stress echocardiography (DSE) provides an objective assessment of the presence and extent of coronary artery disease. Therefore we compared cardiac outcome in patients at high-cardiac risk undergoing open or endovascular repair of infrarenal AAA using preoperative DSE results.
Methods:
Consecutive patients with >or=3 cardiac risk factors (age >70 years, angina pectoris, myocardial infarction, heart failure, stroke, renal failure, and diabetes mellitus) undergoing infrarenal AAA repair were reviewed retrospectively. All underwent cardiac stress testing using DSE. Postoperatively data on troponin release and ECG were collected on day 1, 3, 7, before discharge, and on day 30. The main outcome measures were perioperative myocardial damage and myocardial infarction or cardiovascular death.
Results:
All 77 patients (39 endovascular, 38 open) had a history of cardiac disease. The number and type of cardiac risk factors were similar in both groups. Also DSE results were similar: 55 vs 56%, 24 vs 28%, and 21 vs 18% had no, limited, or extensive stress induced myocardial ischemia respectively. The incidence of perioperative myocardial damage (47% vs 13%, p=0.001) and the combination of myocardial infarction or cardiovascular death (13% vs 0%, p=0.02) was significantly lower in patients receiving endovascular repair.
Conclusion:
In patients with similar high cardiac risk, endovascular repair of infrarenal aortic aneurysms is associated with a reduced incidence of perioperative myocardial damage.
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