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Ocular wavefront aberrations in patients after diffuse lamellar keratitis
Sandra Maria Canelas Beer1, Mauro Campos, Paraguassu Tibiriçá Lopes
1Refractive Surgery Center, Department of Ophthalmology, Federal University of São Paulo, Brazil. sandrabeer@uol.com.br
Cornea
|January 2, 2007
Summary
Diffuse lamellar keratitis (DLK) after laser in situ keratomileusis (LASIK) may alter ocular wavefront aberrations. However, DLK occurrence may not significantly impact overall visual outcomes in LASIK patients.
Area of Science:
- Ophthalmology
- Refractive Surgery
- Corneal Aberrations
Background:
- Laser in situ keratomileusis (LASIK) is a common refractive surgery.
- Diffuse lamellar keratitis (DLK) is a potential complication following LASIK.
- Understanding the impact of DLK on visual quality is crucial.
Purpose of the Study:
- To investigate ocular wavefront aberrations in patients who developed DLK after LASIK.
- To compare aberration profiles between DLK patients and uneventful LASIK controls.
Main Methods:
- A case-control study involving 47 patients with DLK and 30 controls.
- Measurements included visual acuity, refraction, corneal topography, and ocular wavefront aberrations (LADARWAVE aberrometer).
- All LASIK procedures utilized standardized microkeratome and excimer laser systems.
Main Results:
- A statistically significant difference in high-order aberration S7+7 was observed in the DLK group (P=0.015).
- Aberrations S3+3 and S8+4 showed a tendency towards differences between groups.
- Patients with DLK experienced a greater loss of best-corrected visual acuity.
Conclusions:
- DLK following LASIK can lead to specific changes in ocular wavefront aberrations.
- Despite aberration changes, the overall visual outcome in patients with DLK may not be significantly compromised.
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