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Segmentation of the gallbladder: effect on bile entry and exit and its clinical relevance in a patient with abdominal
Gerbail T Krishnamurthy1, Shakuntala Krishnamurthy, Thomas Milleson
1Department of Nuclear Medicine, Tuality Community Hospital, 335 SE 8th Avenue, Hillsboro, OR, USA. GTKrishna@aol.com
Background:
The effects of folds or septa on gallbladder filling and emptying are not known.
Methods:
Gallbladder filling and emptying were measured in seven patients with two chambers (segmental) and compared with 10 subjects with a single chamber (control). Percent bile flow into gallbladder, and percent ejection fraction from the proximal and distal segments, and entire gallbladder were measured with cholecystokinin.
Results:
Bile entry into gallbladder was similar in both groups. In patients with segmentation, overall emptying was low mostly due to poor emptying of the distal segment.
Conclusion:
Segmentation of the gallbladder does not affect bile entry, but acting as a one-way valve, a fold or septum lowers emptying significantly, mostly from the distal segment.
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