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Related Concept Videos

Raman Spectroscopy: Overview01:20

Raman Spectroscopy: Overview

The underlying principle of Raman spectroscopy is based on the interaction between light and matter, specifically molecules' inelastic scattering of photons. When a monochromatic beam of light, typically from a laser source, interacts with a sample, most scattered light has the same frequency as the incident light. This is known as Rayleigh scattering.
However, a small fraction of the scattered light exhibits a frequency shift due to the exchange of energy between the incident photons and the...
Raman Spectroscopy Instrumentation: Overview01:26

Raman Spectroscopy Instrumentation: Overview

A conventional Raman spectrophotometer includes a laser source, a sample holding system, a wavelength selector, and a detector.
The monochromatic laser source, typically using visible or near-infrared radiation, generates a highly focused beam of light. This light interacts with the molecules of the sample, scattering some of the light. Liquid and gaseous samples are usually tested in ordinary glass capillaries, while solids can be analyzed as powders packed in capillaries or as potassium...
Atomic Spectroscopy: Absorption, Emission, and Fluorescence01:23

Atomic Spectroscopy: Absorption, Emission, and Fluorescence

Atomic spectroscopy is a vital tool in elemental analysis, both qualitatively and quantitatively. It can be broadly divided into optical spectroscopy, mass spectroscopy, and X-ray spectroscopy methods. The optical spectroscopic methods are atomic absorption spectroscopy (AAS), atomic emission spectroscopy (AES), and atomic fluorescence spectroscopy (AFS). The first step in all three methods is atomization, where the solid, liquid, or solution-phase samples are converted into gas-phase atoms and...

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Related Experiment Video

Updated: Jul 17, 2026

Resonance Raman Spectroscopy of Extreme Nanowires and Other 1D Systems
07:44

Resonance Raman Spectroscopy of Extreme Nanowires and Other 1D Systems

Published on: April 28, 2016

Towards atomic site-selective sensitivity in tip-enhanced Raman spectroscopy.

Norihiko Hayazawa1, Hiroyuki Watanabe, Yuika Saito

  • 1Nanophotonics Laboratory, RIKEN, Wako, Saitama 351-0198, Japan. hayazawa@riken.jp

The Journal of Chemical Physics
|January 4, 2007
PubMed
Summary

Tip-enhanced near-field Raman spectroscopy can detect molecules at the atomic level. Researchers observed specific molecular vibrations, confirming calculations for atomic site-selective detection.

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Last Updated: Jul 17, 2026

Resonance Raman Spectroscopy of Extreme Nanowires and Other 1D Systems
07:44

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Published on: April 28, 2016

Ultrafast Time-resolved Near-IR Stimulated Raman Measurements of Functional π-conjugate Systems
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Single-Molecule Surface-Enhanced Raman Scattering Measurements Enabled by Plasmonic DNA Origami Nanoantennas
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Area of Science:

  • Surface science
  • Spectroscopy
  • Computational chemistry

Background:

  • Tip-enhanced near-field Raman spectroscopy (TERS) offers high spatial resolution for molecular analysis.
  • Understanding molecule-surface interactions is crucial for nanoscale chemical detection.

Purpose of the Study:

  • To investigate the potential of TERS for atomic site-selective detection of adenine.
  • To explore the formation and vibrational properties of silver-adenine isomers.

Main Methods:

  • Computational modeling of silver-adenine interactions and vibrational modes.
  • Experimental TERS measurements to observe specific vibrational modes and spectral shifts.

Main Results:

  • Observed distinct vibrational modes for silver-adenine isomers, not present in isolated adenine.
  • Experimental results showed good agreement with theoretical vibrational calculations.

Conclusions:

  • TERS demonstrates potential for achieving atomic site-selective detection sensitivity.
  • The study validates the formation of specific silver-adenine isomers with unique vibrational fingerprints.