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Interactions of macrophages and monocytes with granulocytes in asthma
L A Burke1, J R Wilkinson, C J Howell
1Dept of Allergy and Allied Respiratory Disorders, UMDS, Guy's Hospital, London, UK.
The European Respiratory Journal. Supplement
|April 1, 1991
Abstract:
The pathology of bronchial asthma demonstrates a multicellular process. The airway mucosa is infiltrated with both mononuclear cells and granulocytes, of which the eosinophil is particularly prominent. In an attempt to further the understanding of the interactions between different cells, we have elected to study the effects of monocyte/macrophage-derived cell products on granulocytes, because of the evidence for monocyte/macrophage activation in bronchial asthma.