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Localization of hepatitis C virus (HCV) antigen by immunohistochemistry on fixed-embedded liver tissue
D Infantolino1, F Bonino, A R Zanetti
1Servizio di Anatomia ed Istologia, Ospedale di Castelfranco Veneto, Torino, Italy.
Abstract:
An immunohistochemical method of staining HCV-related antigens in fixed-embedded liver biopsies is described. Two primary antisera were used: 1) a high titre anti-HCV human IgG separated from an anti-HCV positive serum; and 2) rabbit anti-HCV antibodies. In our experience this method proves to be reproducible and shows a good correlation with serologic results.