Related Experiment Video
Updated: Jul 17, 2026

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
Published on: September 5, 2017
[Epidemiology of childhood tuberculosis in Libreville, Gabon from 1997 to 2001]
E Engohan Alloghe1, M Toung Mve, S Ramarojoana
1Departement de Pidiatrie, Facultd de Medecine et des Sciences de la Santé, Libreville, Gabon.
Abstract:
The purpose of this retrospective study was to determine the epidemiological features of tuberculosis patients under the age of 15 years treated at the Tuberculosis Control Center in Libreville, Gabon from 1997 to 2001 as a basis for improving management. Study criteria included age, sex, BCG vaccination status, social level, type of tuberculosis, HIV status and outcome of treatment. Statistical analysis was performed using EPI INFO software. The childhood tuberculosis rate was 9% with a sex ratio of 1.02 and the most common age group was 0 to 4 years. Three fourths of children were from poor zones and 90% had received BCG vaccination. The incidence of tuberculosis did not increase from year to year. The location of tuberculosis was pulmonary in 77% of cases (n=433) and extrapulmonary in 23% (n=129). No case involving meningitis or miliary disease was observed. Sputum bacilloscopy was positive in 21% of cases involving pulmonary tuberculosis and HIV serology was positive in 4.4% of children tested. The success rate was 54%. Tuberculosis-related mortality was 0.7% but 37% of children were lost from follow-up. Efforts to control tuberculoses by screening children exposed to bacilliferous conditions and vaccinating newborns must be continued. Treatment for tuberculosis must be given free of charge and under medical supervision as recommended by the World Health Organization.
Related Concept Videos
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Tuberculosis
Pulmonary Tuberculosis II
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pulmonary Tuberculosis V
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Pulmonary Tuberculosis III
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis IV
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...

