Iatrogenic limb ischemia caused by angiography closure devices
Related Experiment Video
Updated: Jul 17, 2026

Preclinical Model of Hind Limb Ischemia in Diabetic Rabbits
Published on: June 2, 2019
Chris Derham1, John F Davies, Raashid Shahbazi
1Leeds Vascular Institute, Leeds General Infirmary, Great George Street, Leeds, United Kingdom. cderham@doctors.org.uk
Abstract:
Described are 2 cases of lower limb ischemia that resulted after deployment of 2 different arterial closure devices. One patient presented acutely with lower limb ischemia after an Angio-Seal (St Jude Medical, Minnetonka, Minn) device deployed at the conclusion of cerebral artery aneurysm embolization. The second patient, who underwent angioplasty for aortic recoarctation, presented with claudication 1 week after deployment of the Perclose (Perclose, Redwood City, Calif) device. The use of such devices can result in significant complications, and cardiologists, interventional radiologists, and vascular surgeons are advised to have a high index of suspicion for such complications and work in close conjunction to provide prompt and adequate treatment.
Related Concept Videos
Peripheral Artery Disease V: Postoperative Nursing Management
Cardiac Catheterization I: Pre-Procedure Overview
Aneurysm III: Interprofessional Care
Peripheral Artery Disease III: Interprofessional Care
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Cardiac Catheterization IV: Nursing Management

