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Related Experiment Videos

New developments in the InterPro database.

Nicola J Mulder1, Rolf Apweiler, Teresa K Attwood

  • 1EMBL Outstation-European Bioinformatics Institute Hinxton, Cambridge, UK. mulder@ebi.ac.uk

Nucleic Acids Research
|January 5, 2007
PubMed
Summary

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This summary is machine-generated.

InterPro is a protein signature database resource integrating multiple databases for protein family, domain, and functional site analysis. Recent updates enhance its utility with new features and broader protein coverage.

Area of Science:

  • Bioinformatics
  • Computational Biology
  • Molecular Biology

Background:

  • InterPro is a comprehensive resource for protein families, domains, and functional sites.
  • It integrates data from multiple protein signature databases, including newly added Gene3D and PANTHER.
  • Previous versions provided matches to UniProtKB proteins and XML files.

Purpose of the Study:

  • To report on recent developments and updates to the InterPro resource.
  • To highlight the integration of new member databases and expanded data accessibility.
  • To announce the availability of additional protein match data for UniParc.

Main Methods:

  • Integration of Gene3D and PANTHER databases into the InterPro resource.
  • Development of new features including an additional reading field and enhanced web interface.

Related Experiment Videos

  • Expansion of data output to include additional match XML files for UniParc proteins.

    • Main Results:

    • The latest release (13.0) includes over 13,000 entries, covering 78% of UniProtKB proteins.
    • New match XML files provide additional matches to UniParc proteins.
    • InterProScan is now accessible via a web service.

    Conclusions:

    • InterPro continues to expand its integrated protein signature data.
    • Recent updates improve data accessibility and resource utility for researchers.
    • The resource supports comprehensive protein analysis through web and FTP access.