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[The relationship between the neuroendocrine system and juvenile chronic arthritis: a hypothesis]
C J Heijnen1, A Kavelaars, W Kuis
1Afd. Pediatrische Immunologie en Reumatologie, Universiteitskliniek voor kinderen en jeugdigen, Het Wilhelmina Kinderziekenhuis, Utrecht.
Tijdschrift Voor Kindergeneeskunde
|October 1, 1991
Abstract:
During the last decennium it has become clear that the course of an inflammatory reaction is not only governed by the immune system. In this paper we describe which other organ systems than the immune system may influence chronic inflammatory responses such as observed in Juvenile Chronic Arthritis (JCA). Attention will be focussed on the role of glucocorticoids, catecholamines and of the neurotransmitter substance P.