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Updated: Jul 17, 2026

09:39
Technique to Collect Fungiform (Taste) Papillae from Human Tongue
Published on: September 18, 2010
First-bite syndrome after resection of the styloid process
Claudio R Cernea1, Flávio C Hojaij, Dorival De Carlucci
1Department of Head and Neck Surgery, University of São Paulo Medical School, São Paulo, Brazil. cerneamd@uol.com.br
The Laryngoscope
|January 5, 2007
Summary
First-bite syndrome (FBS) can occur after surgery for Eagle syndrome. This case highlights successful pain management with carbamazepine, emphasizing long-term medication for this rare complication.
Area of Science:
- Otolaryngology
- Neurosurgery
- Pain Management
Background:
- First-bite syndrome (FBS) is characterized by sharp pain triggered by the initial bites of meals.
- It is a known complication following surgeries involving the parapharyngeal space.
Observation:
- A 51-year-old woman presented with neck pain, diagnosed with Eagle syndrome due to a hypertrophic styloid process (SP).
- Following surgical excision of the SP, she developed FBS, experiencing pain with the first bite of each meal.
Findings:
- The patient's FBS was effectively managed with carbamazepine 800 mg daily.
- Discontinuation of medication after two years resulted in no relapse of symptoms.
Implications:
- This case is the first to report FBS subsequent to surgical treatment for Eagle syndrome.
- Highlights the importance of considering FBS in postoperative patients and the potential need for prolonged, specific pharmacotherapy.
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