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Updated: Jul 17, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
Atypical lung involvement in a patient with systemic juvenile xanthogranuloma
Baris Bakir1, Emin Unuvar, Ege Terzibasioglu
1Department of Radiology, Istanbul Medical School, Istanbul University, 34390 Capa, Turkey. drbarisbakir@yahoo.com
Abstract:
Juvenile xanthogranuloma (JXG) is a non-Langerhans cell histiocytosis characterized by xanthoma-like cutaneous lesions. It is a benign condition that is generally asymptomatic. Visceral involvement is uncommon, but when present may occur in various locations and in different combinations. Pulmonary involvement has been reported as bilateral, multiple micro- or macronodular lesions. We present a 10-year-old boy with systemic (skin, lung, liver and kidney) JXG who showed lung involvement with mainly an interstitial pattern. Bilateral multiple micronodules in both lungs and mediastinal adenopathy were also present.
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