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Updated: Jul 17, 2026
04:38
A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats
Published on: May 22, 2019
[Depression and stroke: an up-to-date review]
Pierluigi Politi1, Paola Sciarini, Giovanni Segagni Lusignani
1DSSAeP, Sezione di Psichiatria, Universittà di Pavia, Pavia. pierluigi.politi@unipv.it
Epidemiologia E Psichiatria Sociale
|January 6, 2007
Summary
Post-stroke depression (PSD) is common and linked to increased stroke risk. Antidepressants can treat PSD, but complete remission is challenging, highlighting the need for psychiatric attention.
Area of Science:
- Neurology
- Psychiatry
- Epidemiology
Context:
- Depression following a stroke is a frequent occurrence.
- Stroke incidence is higher in depressed individuals than expected by chance.
- Underdiagnosis of post-stroke depression is a significant concern.
Purpose:
- To define the epidemiological and clinical characteristics of Post Stroke Depression (PSD).
- To evaluate the available treatment options for PSD.
Summary:
- Systematic and manual searches of the Medline database (2000-2004) were conducted.
- Antidepressants demonstrate efficacy in treating PSD, though achieving full remission remains difficult.
- Disability and compromised quality of life are common consequences of stroke and subsequent depression.
Impact:
- Establishes the significant link between stroke and depression, warranting further psychiatric research.
- Highlights the need for improved diagnostic strategies and treatment approaches for PSD.
- Emphasizes the impact of PSD on patient and family well-being.
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