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Updated: Jul 17, 2026

In vivo Characterization of Endocrine Disrupting Chemical Effects via Thyroid Hormone Action Indicator Mouse
Published on: October 6, 2023
Thyroid hormones concentrations and ECG picture in the dog
U Pasławska1, A Noszczyk-Nowak, K Kungl
1Department of Internal and Parasitic Diseases with Clinic for Horses, Dogs and Cats, Faculty of Veterinary Medicine, Wrocław University of Agriculture, pl. Grunwaldzki 47, 50-366 Wrocław, Poland. ula@ozi.ar.wroc.pl
Thyroid disorders significantly impact canine heart function. Hypothyroidism in dogs slows heart rate and impairs electrical signal conduction, as shown by electrocardiogram (ECG) changes.
Area of Science:
- Veterinary Medicine
- Endocrinology
- Cardiology
Background:
- Thyroid gland disorders are common endocrine issues in dogs.
- Hypothyroidism and hyperthyroidism can negatively affect the cardiovascular system, potentially causing arrhythmias.
- Evaluating thyroid activity's impact on canine ECGs is crucial for understanding cardiac disturbances.
Purpose of the Study:
- To assess the influence of thyroid gland activity on the electrocardiogram (ECG) in dogs.
- To compare ECG findings in healthy dogs, dogs with hypothyroidism, and dogs with cardiac insufficiency due to mitral valve endocardiosis.
Main Methods:
- The study involved 38 dogs divided into three groups: healthy controls, dogs with cardiac insufficiency, and dogs with hypothyroidism.
- Clinical examinations included history, physical, cardiological assessments (ECG, heart USG), and laboratory tests (lipids, thyroid hormones T3, T4, FT4).
Main Results:
- Thyroid activity significantly influences the ECG in dogs.
- Hypothyroidism was associated with decreased sino-atrial node activity and a slower heart rate.
- Dogs with hypothyroidism exhibited reduced intra-cardiac conduction, evidenced by prolonged P wave, QRS complex, and QT interval on ECG.
Conclusions:
- Thyroid dysfunction, particularly hypothyroidism, demonstrably alters cardiac electrical activity in dogs.
- ECG analysis is a valuable tool for detecting cardiac changes associated with thyroid disorders in canine patients.
- These findings highlight the importance of considering thyroid status in the diagnosis and management of canine heart disease.
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