Mosaicing of microscope images with global geometric and radiometric corrections

Image mosaicing has found a number of applications such as panoramic imaging, digital terrain mapping, ophthalmology and virtual microscopy. In this study, we present an automated mosaicing technique for generating virtual slides from microscope images. We carried out robust image feature matching and global geometric and radiometric parameter estimation. The input images were transformed using the estimated geometric and radiometric parameters and mosaiced together, producing accurate registration of overlapping regions without visible seams.