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Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...

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Related Experiment Video

Updated: Jul 17, 2026

In Vivo Model for Testing Effect of Hypoxia on Tumor Metastasis

In Vivo Model for Testing Effect of Hypoxia on Tumor Metastasis

Published on: December 9, 2016

Juvenile Ewing sarcoma presenting as a pelvic mass.

Tahira Naru¹, Fauzia Haq Nawaz, Javed Rizvi

¹Department of Obstetrics and Gynecology, The Aga Khan University Hospital, Karachi.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

|January 6, 2007

Summary

A rare pelvic Ewing's sarcoma was diagnosed in a teenage girl presenting with leg weakness and weight loss. Multidisciplinary treatment including surgery, chemotherapy, and physiotherapy led to an effective response.

Related Experiment Videos

Last Updated: Jul 17, 2026

In Vivo Model for Testing Effect of Hypoxia on Tumor Metastasis

In Vivo Model for Testing Effect of Hypoxia on Tumor Metastasis

Published on: December 9, 2016

Area of Science:

Oncology
Pediatric Oncology
Sarcoma Research

Background:

Ewing sarcoma is a rare bone cancer, but non-osseous origins are exceptionally uncommon.
Pelvic Ewing sarcoma presents diagnostic challenges, particularly in adolescents.

Observation:

A teenage girl presented with rapid pelvic mass development, unintended weight loss, and left leg weakness.
Clinical evaluation revealed a non-osseous Ewing sarcoma originating in the pelvis.

Findings:

The rare pelvic Ewing sarcoma was treated using a comprehensive, multidisciplinary approach.
Treatment modalities included surgical resection, chemotherapy, and intensive physiotherapy for rehabilitation.
The patient demonstrated an effective response to the combined treatment strategy.

Implications:

This case highlights the importance of considering rare presentations of Ewing sarcoma.
A multidisciplinary approach is crucial for managing complex pediatric cancers.
Early diagnosis and tailored treatment can lead to favorable outcomes in rare sarcomas.