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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
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Updated: Jul 17, 2026

Functional Magnetic Resonance Imaging (fMRI) of the Visual Cortex with Wide-View Retinotopic Stimulation
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Tilted optic discs visualized by magnetic resonance imaging.

Michelle E Tarver-Carr1, Neil R Miller

  • 1Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA.

Journal of Neuro-Ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society
|January 6, 2007
PubMed
Summary

A young woman

Area of Science:

  • Ophthalmology and Neurology
  • Neuroimaging and Diagnostic Techniques

Background:

  • Headaches can be a symptom of increased intracranial pressure.
  • Papilledema, or swelling of the optic disc, is a key sign of such pressure.
  • Differentiating true papilledema from other optic disc anomalies is crucial.

Observation:

  • A young woman presented with headaches and signs of papilledema.
  • Magnetic Resonance Imaging (MRI) of the brain revealed no intracranial abnormalities.
  • Orbital MRI identified specific features in the left eye.

Findings:

  • The orbital MRI demonstrated oblique optic nerve insertion and posterior nasal globe flattening.
  • These findings are characteristic of congenitally tilted optic discs.
  • This case highlights the utility of orbital MRI in diagnosing optic disc anomalies.

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Implications:

  • Congenitally tilted optic discs can mimic papilledema, leading to potential misdiagnosis.
  • Orbital MRI is a valuable tool for visualizing optic nerve and globe morphology.
  • Accurate diagnosis prevents unnecessary investigations for intracranial pathology.