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Published on: May 27, 2021
[Bioinformatics and GenEnv database in biological risk management].
Vincenzo Romano Spica1, Daniele Santoni, Andrea Paparini
1IUSM: Istituto Universitario di Scienze Motorie, Dipartimento Scienze Movimento Umano e Sport-Sezione di Igiene, Roma. vrs@iusm.it
Igiene E Sanita Pubblica
|January 9, 2007
Summary
The GenEnv database simplifies microbial identification using genetic sequencing data. This user-friendly tool aids biological risk management and scientific research by organizing vast amounts of sequence information.
Area of Science:
- Microbiology
- Bioinformatics
- Genetics
Context:
- Molecular techniques for microbial identification require detailed genetic knowledge.
- Automated sequencing has accelerated data generation and improved accuracy.
- Bioinformatics tools are crucial for managing large sequencing datasets but can be complex to learn.
Purpose:
- To develop a user-friendly bioinformatics tool for sequence analysis.
- To support operators in biological risk management.
- To facilitate microbe identification and research protocol development.
Summary:
- The GenEnv database provides a centralized resource for microbial genetic information.
- It contains over 20,000 sequence records representing more than 9,000 bacterial species.
- Key genes include 16S rDNA, rpoB, and gyrB, with graphical nucleotide sequence representation.
Impact:
- Enhances the ease of microbial identification from environmental samples.
- Streamlines the process of developing research protocols for specific microbial species.
- Offers a valuable resource for public health professionals and scientific researchers in microbiology and related fields.
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