A statistical method for the comparison of a discrete diagnostic test with several continuous diagnostic tests
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Updated: Aug 28, 2026

Evaluation of a Point-of-Care Testing Analyzer for Measuring Peripheral Blood Leukocytes
Published on: March 22, 2022
1Department of Radiology, Duke University Medical Center, Durham, North Carolina 27710.
Abstract:
In this paper we study a statistic that is suitable for comparing a discrete diagnostic marker to one or more continuous diagnostic markers. Test procedures and confidence intervals are based on asymptotic normality. The statistic is applicable for correlated data in which all the markers are obtained for each subject. The statistic was studied for use in comparing two markers for rectal bleeding. Examples for this application and two more general applications are presented.
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