Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Eosinophilic pneumonia induced by daptomycin.

Don Hayes1, Michael I Anstead, Robert J Kuhn

  • 1Department of Pediatrics, University of Kentucky College of Medicine, J410 Kentucky Clinic, Lexington, KY 40536, USA. don.hayes@uky.edu <don.hayes@uky.edu>

The Journal of Infection
|January 9, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Lung Transplantation for Pulmonary Alveolar Proteinosis - a Retrospective International Multi-Center Analysis.

The European respiratory journal·2026
Same author

The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: 2026 Annual Pediatric Heart Transplantation Report, Trends and Post-transplant Outcomes by Recipient Sex.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2026
Same author

Cryotherapy via flexible bronchoscopy: the role of cryobiopsy in pediatric lung transplantation.

Annals of the American Thoracic Society·2026
Same author

The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: 2026 Adult Heart Transplantation: A Contemporary Analysis of Trends and Outcomes by Recipient Sex.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2026
Same author

A Perspective Summary of the ISHLT Consensus Statement on Acute Lung Allograft Dysfunction (ALAD).

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2026
Same author

ISHLT Consensus Statement on Acute Lung Allograft Dysfunction (ALAD): Definition, Etiology, Diagnostic and Therapeutic Approaches, and Research Priorities.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2026

A patient developed severe lung injury from the antibiotic daptomycin, a rare drug-induced eosinophilic pneumonia. Prompt withdrawal of daptomycin and corticosteroid treatment led to rapid recovery and mechanical ventilation discontinuation.

Area of Science:

  • Pulmonology
  • Infectious Diseases
  • Pharmacology

Background:

  • Recurrent methicillin-sensitive Staphylococcus aureus endocarditis necessitates effective antibiotic therapy.
  • Intravenous daptomycin is a treatment option for complex Staphylococcal infections.

Observation:

  • A patient receiving intravenous daptomycin for Staph aureus endocarditis developed acute hypoxic respiratory failure.
  • The respiratory failure necessitated mechanical ventilation, indicating severe lung injury.

Findings:

  • The condition was diagnosed as drug-induced eosinophilic pneumonia attributed to daptomycin.
  • Cessation of daptomycin therapy and administration of corticosteroids resulted in significant clinical improvement.

Implications:

Related Experiment Videos

  • This case highlights a rare but serious adverse pulmonary reaction to daptomycin.
  • Early recognition and management with corticosteroids are crucial for favorable outcomes in daptomycin-induced lung injury.