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Combined Supine and Standing Imaging for Varicocele: An Improved Diagnostic Approach
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Supernumerary minute ring chromosome 14 in a man with primary infertility and left varicocele
Brandon C Stahl1, Shivanand R Patil, Craig H Syrop
1Department of Urology, University of Iowa, Iowa City, Iowa 52242-1089, USA.
Objective:
To describe a case of supernumerary minute ring chromosome (SMRC) in an infertile man, with the concurrent finding of a left varicocele.
Design:
Case report.
Setting:
Urologic infertility clinic in a university hospital.
Patient(S):
Male patient presenting with primary infertility.
Intervention(S):
Karyotyping, genetic counseling, and microsurgical left varicocelectomy.
Main Outcome Measure(S):
Sperm concentration and motility, chromosomal number and structure.
Result(S):
Fluorescence in situ hybridization revealing SMRC 14. Sperm concentration and motility improved after left varicocele repair.
Conclusion(S):
A karyotype should be included in the evaluation of severe oligospermia. Although SMRC 14 may be associated with fertility problems, repair of a coexisting varicocele should be considered in these patients.
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