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A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations
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Robert E. Gross Lecture. Fetomaternal cell trafficking: a story that begins with prenatal diagnosis and may end with

Diana W Bianchi1

  • 1Division of Genetics, Department of Pediatrics, The Floating Hospital for Children and Tufts-New England Medical Center, Boston, MA 02111, USA. dbianchi@tufts-nemc.org

Journal of Pediatric Surgery
|January 9, 2007
PubMed
Abstract

No abstract available in PubMed .

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Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...