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Updated: Jul 17, 2026

Experimental Protocol for Detecting Mitochondrial Function in Hepatocytes Exposed to Organochlorine Pesticides
Published on: September 16, 2020
Case study on chronic organophosphate poisoning
M G Robson1, G C Hamilton, G O Brachman
1UMDNJ--School of Public Health, Piscataway, NJ 08854, USA.
Abstract:
Ernest and Leslie Rea, two farmers in their mid-fifties, contacted their local County Agricultural Extension Office in Cape May, New Jersey, regarding health problems associated with their use of pesticides. They were referred to Dr. Hamilton and the Environmental and Occupational Health Sciences Institute (EOHSI) clinic for consultation and evaluations. They were diagnosed with chronic intoxication of organophosphate pesticides. Recommendations were made to decrease health risks in the farming operations. These included the usage of personal protective equipment while handling or applying pesticides, transportation of pesticides in a separate trailer behind the farm truck, and construction of separate storage areas for herbicides, insecticides and fungicides. A separate wash site was also constructed for use at the end of the work day. Compliance with these strategies resulted in improvements in health for both farmers.
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