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Updated: Jul 17, 2026

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder
Published on: April 26, 2024
A practical screening tool for anxiety and depression in patients with chronic breathing disorders
Mark E Kunik1, Pierre N Azzam, Julianne Souchek
1Houston Center for Quality of Care and Utilization Studies, Health Services Research and Development Service, Michael E DeBakey Veteran Affairs Medical Center (152), 2002 Holcombe, Houston, TX 77030, USA. mkunik@bcm.tmc.edu
Abstract:
Obstructive lung diseases are associated with high rates of depression and anxiety, yet many patients are never screened or treated. This study evaluated the five-question Depression and Anxiety modules of the Primary Care Evaluation of Mental Disorders (PRIME-MD) Patient Questionnaire as a telephone screen in 1,632 patients with chronic breathing disorders at a Veterans Affairs Medical Center in Houston, TX. Subsequent testing of 828 patients with the Beck Depression Inventory-II and the Beck Anxiety Inventory showed that the sensitivity and specificity, respectively, of the Depression and Anxiety modules of the PRIME-MD Patient Questionnaire screening were 94.6% and 49.5% (Depression); 93.7% and 32.2% (Anxiety); and 97.7%, and 36.0% (combined screen), with an overall accuracy of 80.7%. In such populations, these two modules of the PRIME-MD Patient Questionnaire may be a useful screening tool.
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