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[Lichen sclerosus in urological practice].

Peter Nyirády1, Katalin Borka, Gergely Bánfi

  • 1Semmelweis Egyetem, Altalános Orvostudományi Kar, Urológiai Klinika, Budapest. nyiradyp@hotmail.com

Orvosi Hetilap
|January 11, 2007
PubMed
Summary

Lichen sclerosus is frequently found in adult phimosis and recurrent urethral strictures. This condition is also present in a third of penile squamous cell carcinoma cases, suggesting a link to malignancy.

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Area of Science:

  • Urology
  • Dermatology
  • Oncology

Context:

  • Lichen sclerosus is an inflammatory skin condition with unknown etiology.
  • It commonly leads to secondary phimosis and urethral strictures.
  • Long-term lichen sclerosus increases the risk of squamous cell neoplasia.

Purpose:

  • To determine the role of lichen sclerosus in adult phimosis.
  • To categorize urological treatments for lichen sclerosus.
  • To define optimal therapy for meatal and urethral strictures caused by lichen sclerosus.
  • To assess the incidence of lichen sclerosus in patients with squamous cell neoplasia.

Summary:

  • Histological examination of 123 foreskins from circumcised patients revealed lichen sclerosus in 62%.
  • Lichen sclerosus was identified in 90% of excised tissues from recurrent urethral strictures.

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  • The condition was present in 33% of penile squamous cell carcinoma cases.

    • Impact:

    • Lichen sclerosus is a significant factor in adult phimosis.
    • It is a frequent cause of recurrent urethral strictures, often requiring complex reconstructive surgery.
    • The high incidence in squamous cell carcinoma cases highlights its potential role in malignant transformation.