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Related Concept Videos

Structure and Function of Platelets01:18

Structure and Function of Platelets

The cell fragments known as platelets are disc-shaped, with an average diameter of about 3 μm and a thickness of roughly 1 μm. They play a crucial role in the body's vascular clotting system, which also involves plasma proteins, blood cells, and blood vessel tissues.
Platelets are continually replenished, circulating in the bloodstream for 9-12 days before being removed by phagocytes, primarily in the spleen. A microliter of circulating blood contains between 150,000 and 450,000 platelets, with...
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The platelet phase, the second stage of hemostasis, commences around 15-20 seconds after an injury. It follows and overlaps with the vascular phase, during which blood vessels constrict to minimize blood loss.
As the injured blood vessel contracts, endothelial cells undergo contraction, revealing collagen fibers in the basement membrane and underlying connective tissue. Furthermore, the plasma membrane of endothelial cells becomes adhesive, preparing the site for platelet adhesion. Platelets...
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Satellite Stem Cells and Muscular Dystrophy

Satellite stem cells or myosatellite cells are quiescent stem cells that Alexander Mauro first identified in 1961. These cells are located between the sarcolemma, the plasma membrane of muscle fibers, and the basal lamina, the connective tissue sheath covering it. These mononucleated cells are activated in response to muscle injury, can transform into myoblasts, and may form or repair muscle fibers. Myosatellite cells can provide additional myonuclei for muscle regeneration or return to a...

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Related Experiment Video

Updated: Jul 17, 2026

Procoagulant Platelet Characterization by Measuring Phosphatidylserine Exposure and Microvesicle Release from Human Purified Platelets
05:49

Procoagulant Platelet Characterization by Measuring Phosphatidylserine Exposure and Microvesicle Release from Human Purified Platelets

Published on: November 29, 2024

[Platelet satellitism].

Edwina Kasprzycka1, Janusz Zak, Karol Ratomski

  • 1Z Zakładu Laboratoryjnej Diagnostyki Pediatrycznej Akademii Medycznej, Białymstoku.

Wiadomosci Lekarskie (Warsaw, Poland : 1960)
|January 11, 2007
PubMed
Summary

Platelet satellitism, where platelets adhere to white blood cells, was observed in a pediatric patient with bronchopneumonia. This phenomenon, though rare, highlights the need for microscopic blood smear examination.

Area of Science:

  • Hematology
  • Clinical Pathology

Background:

  • Platelet satellitism is a rare hematological finding characterized by platelets adhering to leukocytes.
  • This phenomenon can be observed in peripheral blood smears, particularly in EDTA-anticoagulated samples.

Observation:

  • A 12-month-old patient hospitalized for bronchopneumonia presented with platelet satellitism in their peripheral blood smear.
  • Cytometric analysis revealed significant aggregation of platelets with granulocytes (88.7%), monocytes (5.0%), and lymphocytes (17.0%).

Findings:

  • The study observed a gradual decrease in platelet count coinciding with the presence of platelet satellitism.
  • Microscopic examination of blood smears remains crucial for accurate hematological assessment, even with advanced analyzers.

Implications:

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  • Platelet satellitism can affect platelet counts, necessitating careful interpretation of automated hematology results.
  • This case underscores the continued importance of manual blood smear review for diagnosing and understanding hematological disorders.