[Stimulation of proliferative and metabolic processes in the liver after administration of allogeneic hepatocytes]

The interconnection of morpho-functional changes of liver and cellular capacity to synthesize RNA and DNA in condition of the acute liver failure (ALF) and after the administration of the newborn allogenic hepatocytes (NAH) was studied by the autoradiographic method. The administration of NAH prevents, in part, the ischemic cell death and is efficient in the stimulation of the liver regeneration in ALF; it increases metabolic and proliferative activity of hepatocytes as well as of reticulo-endothelial cells.