Related Experiment Video
Updated: Jul 17, 2026

Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice
Published on: June 8, 2022
Lupus and pregnancy: complex yet manageable
Josephine Patricia Dhar1, Robert J Sokol
1Harper University Hospital, MI 48201, USA. PDhar@med.wayne.edu
Abstract:
Systemic lupus erythematosus is a chronic multi-system autoimmune disease that occurs predominantly in women of childbearing age. The risk of complications and adverse fetal outcomes in pregnant women with lupus is high. Moreover, pregnancy can cause flares of lupus disease activity necessitating maternal immunosuppressive intervention. Interestingly, many potential complications of pregnancy present as symptoms of lupus making diagnosis and treatment a challenge. Advancing technology and better understanding of the maternal-fetal dyad in lupus have improved outcomes in lupus pregnancies over the last 40 years. This article will briefly review the important issues in pregnancies complicated by lupus and provide a general guideline to physicians for monitoring and treatment.
Related Concept Videos
Mitral Valve Prolapse III: Nursing Management
Autoimmune Disorders
Concept and Mechanism of Autoimmune Diseases
The immune system...
Teratogenicity
Nephrotic Syndrome II : Assessment and Medical Management
Rheumatic Heart Disease IV: Nursing Management
Rheumatic Heart Disease III: Medical Management