Preparation of amino-functionalized mesostructured cellular foams and application as hosts for large biomolecules

Large mesopores cellular foam (LMCFs) materials were synthesized using microemulsion templating in acidic solutions. The amine functional groups were attached to channels of LMCFs materials via post-synthesis grafting. The structural and chemical properties of these prepared materials were characterized by TEM, XRD, FTIR and nitrogen adsorption. These resulting materials had disordered mesopores with well-defined large mesopore. The bovine serum albumin (BSA) and glucose oxidase (GOx) were used for adsorption experiment. The biomolecule was immobilized by covalently couple to the interior surface of amino-functionalized mesostructured cellular foams (AF-MCFs). The results showed that AF-MCFs had high-capacity bioimmobilization ability.