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Updated: Jul 17, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
Published on: December 11, 2017
[Cardiac resynchronization therapy in patients with permanent atrial fibrillation--with or without atrial lead?]
1J.W. Goethe-Universitätsklinik, Medizinische Klinik III-Kardiologie, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.
Insights
A patient with heart failure improved with cardiac resynchronization therapy (CRT). However, a shock for ventricular tachyarrhythmia worsened his condition, as revealed by ECG.
Area of Science:
- Cardiology
- Electrophysiology
- Medical Devices
Context:
- Severe heart failure and left bundle branch block necessitate biventricular defibrillator implantation for cardiac resynchronization therapy (CRT).
- Patients with permanent atrial fibrillation may not receive an atrial lead during CRT implantation.
- Successful CRT can improve heart failure symptoms, but complications can arise.
Purpose:
- To investigate the cause of symptom deterioration following successful cardiac resynchronization therapy (CRT) and defibrillation in a patient with severe heart failure.
- To analyze the electrocardiogram (ECG) findings that explain the adverse event.
- To highlight potential challenges in managing patients with complex cardiac conditions.
Summary:
- A 59-year-old male with severe heart failure, left bundle branch block, and permanent atrial fibrillation received a biventricular defibrillator for CRT.
- Initial CRT improved symptoms, but a subsequent shock for ventricular tachyarrhythmia led to severe symptom recurrence.
- An ECG performed one week post-shock revealed the underlying reason for the clinical deterioration.
Impact:
- This case underscores the importance of careful ECG interpretation after defibrillation in CRT patients.
- It highlights potential interactions between CRT devices and tachyarrhythmia management.
- Understanding such events can refine patient management strategies and improve outcomes in complex heart failure cases.
Abstract:
A 59-year-old patient received a biventricular defibrillator for cardiac resynchronization therapy (CRT) due to severe heart failure and a left bundle branch block. He had suffered from mitral stenosis and had received valve replacement 16 years earlier. Because he had permanent atrial fibrillation since that time, no atrial lead was implanted. His symptoms improved with CRT until he received adequate shock therapy for a rapid ventricular tachyarrhythmia. After that his symptoms deteriorated again severely. The ECG recorded during an unscheduled follow-up visit 1 week after the shock explains the reason.
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