Methods and application areas of endoscopic optical coherence tomography
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Updated: Jul 17, 2026

Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography
Published on: February 9, 2019
Zahid Yaqoob1, Jigang Wu, Emily J McDowell
1Engineering and Applied Sciences Division, Electrical Engineering Department, California Institute of Technology, Pasadena, California 91125, USA. zyaqoob@caltech.edu
Abstract:
We review the current state of research in endoscopic optical coherence tomography (OCT). We first survey the range of available endoscopic optical imaging techniques. We then discuss the various OCT-based endoscopic methods that have thus far been developed. We compare the different endoscopic OCT methods in terms of their scan performance. Next, we examine the application range of endoscopic OCT methods. In particular, we look at the reported utility of the methods in digestive, intravascular, respiratory, urinary and reproductive systems. We highlight two additional applications--biopsy procedures and neurosurgery--where sufficiently compact OCT-based endoscopes can have significant clinical impacts.
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