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Updated: Jul 17, 2026

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
Published on: May 14, 2013
Stenting and angioplasty of the symptomatic chronically occluded carotid artery
A J Thomas1, R Gupta, A H Tayal
1Department of Neurosurgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Insights
Patients with carotid artery occlusion face high stroke risk. Successful revascularization using angioplasty and stenting offers a new treatment option for these individuals.
Area of Science:
- Neurology
- Vascular Surgery
- Interventional Cardiology
Background:
- Patients with carotid artery occlusion and hemodynamic compromise are at elevated risk for stroke.
- Current treatment options include extracranial-to-intracranial bypass and direct carotid thromboendarterectomy.
Observation:
- Two patients with symptomatic, chronically occluded carotid arteries were treated.
Findings:
- Successful revascularization was achieved in both patients using angioplasty and stenting.
- This demonstrates the feasibility of endovascular treatment for chronic carotid occlusion.
Implications:
- Angioplasty and stenting may represent a viable alternative to surgical revascularization for select patients.
- Further research is warranted to evaluate the long-term efficacy and safety of this endovascular approach.
Abstract:
Patients with hemodynamic impairment ipsilateral to a carotid occlusion are at a high risk of subsequent stroke, and currently 2 surgical options have been studied: extracranial-to-intracranial bypass and direct thromboendarterectomy. We report the successful revascularization of 2 symptomatic chronically occluded carotid arteries with stenting and angioplasty.
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