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Updated: Jul 17, 2026

RhoC GTPase Activation Assay
09:58

RhoC GTPase Activation Assay

Published on: August 22, 2010

Transcriptomal profiling of the cellular transformation induced by Rho subfamily GTPases

I M Berenjeno1, F Núñez, X R Bustelo

  • 1Centro de Investigación del Cáncer and Instituto de Biología Molecular y Celular del Cáncer (IBMCC), CSIC-University of Salamanca, Campus Unamuno, Salamanca, Spain.

Oncogene
|January 11, 2007
PubMed
Summary

Rho subfamily guanosine 5'-triphosphate (GTP)ases orchestrate complex genetic programs in transformed cells, preferentially upregulating proliferation and DNA synthesis genes. c-Myc is essential, but not sufficient, for Rock-dependent cell transformation.

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