Related Experiment Video
Updated: Jul 17, 2026

08:23
Culture Methods to Determine the Limit of Detection and Survival in Transport Media of Campylobacter Jejuni in Human Fecal Specimens
Published on: March 10, 2020
Campylobacter diarrhea in Alexandria, Egypt
G Pazzaglia1, A L Bourgeois, A S Mourad
1Enterics Program, Naval Medical Research Institute, Bethesda MD, USA.
The Journal of the Egyptian Public Health Association
|January 1, 1995
Summary
Campylobacter is a significant cause of bacterial diarrhea in young children in Alexandria, Egypt. This bacterium was more frequently found in ill children than in healthy ones, especially during the rainy season.
Area of Science:
- Pediatric infectious diseases
- Microbiology
- Public health epidemiology
Background:
- Bacterial diarrhea poses a significant health risk to young children globally.
- Understanding the specific causative agents is crucial for effective treatment and prevention strategies.
Purpose of the Study:
- To investigate the role of Campylobacter as a bacterial cause of diarrhea in young children in Alexandria, Egypt.
- To compare the prevalence of Campylobacter with other bacterial pathogens in pediatric diarrhea cases.
Main Methods:
- A case-control study was conducted involving 880 children with diarrhea and 1,079 healthy children.
- Stool or rectal swab samples were collected for bacterial isolation and identification.
- Statistical analysis was performed to determine the significance of Campylobacter isolation rates.
Main Results:
- Campylobacter was isolated from 17.2% of children with diarrhea, significantly higher than the 6.4% isolation rate in healthy controls (p<0.0002).
- Campylobacter was the most frequently isolated bacterial pathogen, exceeding Salmonella (3%), Shigella (2%), and other bacteria (1%).
- Campylobacter isolation rates were significantly higher during the rainy season (p<0.0012).
Conclusions:
- Campylobacter is a major bacterial cause of diarrhea in young children seeking medical attention in Alexandria, Egypt.
- The findings highlight the importance of considering Campylobacter in the diagnosis and management of pediatric diarrhea in this region.
- Seasonal variations may influence the prevalence of Campylobacter infections in children.
Related Concept Videos
Giardiasis
Giardiasis is a globally prevalent intestinal infection caused by the protozoan parasite Giardia duodenalis (also known as G. lamblia or G. intestinalis). This flagellated protozoan is the most frequently identified intestinal parasite in the United States and worldwide. Transmission primarily occurs via the fecal-oral route, with infection arising from ingestion of water or food contaminated with cysts. Individuals in low-resource settings, international travelers, outdoor enthusiasts, daycare...
Bacterial Gastroenteritis
Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...
Amebiasis
Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...
Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents
Acute diarrhea, a common gastrointestinal disturbance, is characterized by the rapid evacuation of fluid stools, leading to an excessive weight in fluid. This condition typically arises from disorders affecting intestinal water and electrolyte transport. It can be triggered by an increased osmotic load within the intestine, excessive secretion of electrolytes and water, mucosal exudation of protein and fluid, or altered intestinal motility. The primary risks of acute diarrhea are dehydration...
Cholera
Cholera is an acute gastrointestinal disease caused by the Gram-negative bacterium Vibrio cholerae. It is transmitted primarily via the fecal-oral route through the ingestion of contaminated water or food.Vibrio cholerae is a motile, Gram-negative bacterium of the family Vibrionaceae, primarily associated with waterborne outbreaks in areas with inadequate sanitation. Although over 200 serogroups of V. cholerae exist, only O1 and O139 are responsible for epidemic cholera. The O1 serogroup,...
Reservoir of Infection
Infectious diseases arise from intricate interactions between pathogens and their reservoirs. A reservoir of infection refers to the natural habitat where a pathogen lives, grows, and multiplies, serving as a continual source of infection. Reservoirs are broadly classified as either living or nonliving, and each plays a unique role in disease transmission, significantly influencing public health interventions and control strategies.Humans act as reservoirs for a wide array of pathogens,...

