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Updated: Jul 17, 2026
Application of the En Bloc Concept Combined with Anatomic Resection in Laparoscopic Hepatectomy
Published on: March 10, 2023
Selection criteria for reduction hepatectomy in multiple advanced hepatocellular carcinoma
Naoto Gotohda1, Hiroshi Ishii, Masaru Konishi
1Department of Hepatobiliary Pancreatic Surgery, National Cancer Center Hospital East, Chiba, 277-8577, Japan. ngotohda@east.ncc.go.jp
Background:
Few studies have compared the prognostic impact of reduction hepatectomy (RH) for advanced hepatocellular carcinoma (HCC) with that of non-surgical treatment or curative hepatectomy.
Patients And Methods:
The treatment outcome of 30 RH patients was compared to that of two control groups: control group A, including 71 patients who underwent curative hepatectomy; control group B, including 106 patients who did not receive definitive local therapy or best supportive care.
Results:
In patients with tumor extension in >50% of the liver, 1-year survival rates for patients according to treatment (RH, control A and B) were 50%, 90% and 11% and 3-year survival rates were 42%, 60% and 0%, respectively. There was no significant difference between RH and control A, but there was a significant difference between RH and control B.
Conclusion:
RH could be recommended to patients with multiple advanced HCC extending to >50% of the whole liver.
