Related Experiment Video

Updated: Jul 17, 2026

PIP-on-a-chip: A Label-free Study of Protein-phosphoinositide Interactions
10:58

PIP-on-a-chip: A Label-free Study of Protein-phosphoinositide Interactions

Published on: July 27, 2017

PDZ domain-phosphoinositide interactions in cell-signaling

P Zimmermann1

  • 1Departement Menselijke Erfelijkheid, Laboratorium voor Glycobiologie en Ontwikkelingsgenetica-KULeuven, Vlaams Interuniversitair Instituut voor Biotechnologie, Herestraat 49, bus 602-B 3000 Leuven.

Verhandelingen - Koninklijke Academie Voor Geneeskunde Van Belgie
|January 12, 2007
PubMed
Summary

PDZ domains, crucial for cell signaling and polarity, can interact with phosphoinositides (PIPs). This lipid binding, exemplified by syntenin proteins and PIP2, reveals a new regulatory mechanism for PDZ domain function.

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