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Echocardiographic Characterization of Left Ventricular Structure, Function, and Coronary Flow in Neonate Mice
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Myocardial tissue velocities in neonates.
Filiz Ekici1, Semra Atalay, Nazire Ozcelik
1Department of Pediatric Cardiology, School of Medicine, University of Ankara, Ankara, Turkey.
Echocardiography (Mount Kisco, N.Y.)
|January 12, 2007
Summary
Neonatal myocardial tissue velocities measured by Tissue Doppler Echocardiography (TDE) are significantly lower than in children, suggesting immature neonatal myocardium. This study provides key reference values for TDE in neonates.
Area of Science:
- Pediatric Cardiology
- Echocardiography
- Neonatal Physiology
Background:
- Tissue Doppler Echocardiography (TDE) is used in children, but neonatal myocardial velocities are underreported.
- Understanding neonatal cardiac function is crucial for early diagnosis and management.
Purpose of the Study:
- To measure and compare longitudinal myocardial velocities in term neonates and healthy children using TDE.
- To establish reference values for neonatal myocardial function.
Main Methods:
- Longitudinal left ventricular myocardial velocities were measured in 50 neonates and 54 children using TDE.
- Measurements were taken at the mitral lateral annulus (MLA), mitral medial annulus (MMA), left ventricular lateral wall (LVLW), and interventricular septum (IVS).
Main Results:
- Myocardial velocities were highest at the MLA in both groups.
- Neonates exhibited significantly lower systolic (Sw), early diastolic (Ew), and atrial systolic velocities (Aw) compared to children.
- The E/Ew ratio was significantly higher in neonates, indicating potential diastolic dysfunction.
Conclusions:
- Neonatal myocardial velocities are significantly lower than in children, likely due to myocardial immaturity.
- These findings highlight the need for age-specific reference ranges for TDE in neonates.
